Some of the important civilizations from ancient Mesopotamia include Sumerians, Akkadians, Assyrians, and Babylonians. While there were many city-states throughout Mesopotamia, some of the important cities included the Sumerian Uruk, Ur, and Nippur.
Sumer was one of the earliest Mesopotamian civilizations in the southern part of Mesopotamia and is believed to have been settled around 4 500 BC to 4 000 BC.
Uruk was considered one of the first “real” city-states when Sumerian civilization became more urbanized. It started around 4 000 BC and lasted until 3 200 BC.
The Sumerian civilization was succeeded by the Akkadians, led by the ruler Sargon of Akkad, from 2334 BC to 2154 BC. After the Akkadian Empire fell, there was a period referred to as a “Dark Age” after which there was a resurgence in Sumerian culture.